Publications
The following links are the publications of the Brivanlou Lab. They correspond in numbering to Dr. Brivanlou’s CV.
1. Brivanlou, A. H., and Harland, R. M. (1989). Expression of an Engrailed-Related Protein Is Induced in the Anterior Neural Ectoderm of Early Xenopus Embryos. Development, 106(3), 611-617.
2. Condie, B. G., Brivanlou, A. H., and Harland, R. M. (1990). Most of the Homeobox-Containing Xhox 36 Transcripts in Early Xenopus Embryos Cannot Encode a Homeodomain Protein. Molecular and cellular biology, 10(7), 3376-3385.
3. Brivanlou, A. H., Frank, D., Bolce, M. E., Brown, B. D., Sive, H. L., and Harland, R. M. (1990). Localization of Specific Mrnas in Xenopus Embryos by Whole-Mount in Situ Hybridization. Development, 110(2), 325-330.
4. Brivanlou, A. H., Stewart, R. M., and Harland, R. M. (1990). Region-Specific Neural Induction of an Engrailed Protein by Anterior Notochord in Xenopus. Science, 250(4982), 800-802.
5. Brivanlou, A. H., de la Torre, J. R., Holt, C., and Harland, R. M. (1991). Cephalic Expression and Molecular Characterization of Xenopus En-2. Development, 111(3), 715-724.
6. Vize, P. D., Melton, D. A., Brivanlou, A. H., and Harland, R. M. (1991). Assays for Gene Function in Developing Xenopus Embryos. Methods in cell biology, 36, 367-387.
7. Bolce, M. E., Brivanlou, A. H., Kushner, P. D., and Harland, R. M. (1992). Ventral Ectoderm of Xenopus Forms Neural Tissue, Including Hindbrain, in Response to Activin. Development, 115(3), 681-688.
8. Brivanlou, A. H., Mann, R. W., and Harland, R. M. (1992). A Protein Expressed in the Growth Cones of Embryonic Vertebrate Neurons Defines a New Class of Intermediate Filament Protein. Neuron, 9(3), 417-428.
9. Brivanlou, A. H., and Melton, D. A. (1992). A Truncated Activin Receptor Inhibits Mesoderm Induction and Formation of Axial Structures in Xenopus Embryos. Nature, 359(6396), 609-614. doi: 10.1038/359609a0
10. Brivanlou, A. H., Wright, D. A., and Melton, D. A. (1992). Embryonic Expression and Functional Analysis of a Xenopus Activin Receptor. Developmental dynamics : an official publication of the American Association of Anatomists, 194(1), 1-11. doi: 10.1002/aja.1001940102
11. Bolce, M. E., Brivanlou, A. H., and Harland, R. M. (1993). Xfkh2, a Xenopus Hnf-3 Alpha Homologue, Exhibits Both Activin-Inducible and Autonomous Phases of Expression in Early Embryos. Developmental biology, 160(2), 413-423. doi: 10.1006/dbio.1993.1317
12. Dohrmann, C. E., Brivanlou, A. H., Thomsen, G. H., Fields, A., Woolf, T. M., and Melton, D. A. (1993). Expression of Activin Mrna During Early Development in Xenopus Laevis. Developmental biology, 157(2), 474-483. doi: 10.1006/dbio.1993.1150
13. Brivanlou, A. H., Kelly, O. G., and Melton, D. A. (1994). Follistatin, an Antagonist of Activin, Is Expressed in the Spemann Organizer and Displays Direct Neuralizing Activity. Cell, 77(2), 283-295.
14. Brivanlou, A. H., and Melton, D. A. (1994). Inhibition of Activin Receptor Signaling Promotes Neuralization in Xenopus. Cell, 77(2), 273-281.
15. Cox, W. G., and Brivanlou, A. H. (1995). Caudalization of Neural Fate by Tissue Recombination and Bfgf. Development, 121(12), 4349-4358.
16. Brivanlou, A. H., and Thomsen, G. H. (1995). Ventral Mesodermal Patterning in Xenopus Embryos: Expression Patterns and Activities of Bmp-2 and Bmp-4. Developmental genetics, 17(1), 78-89. doi: 10.1002/dvg.1020170109
17. Wilson, P. A., and Brivanlou, A. H. (1995). Induction of Epidermis and Inhibition of Neural Fate by Bmp-4. Nature, 376(6538), 331-333. doi: 10.1038/376331a0
18. Henry, G. L., Brivanlou, I. H., Kessler, D. S., Brivanlou, A. H., and Melton, D. A. (1996). Tgf-Β Signals and a Pattern in Xenopus Laevis Endodermal Development. Development, 122(3), 1007-1015.
19. Honore, E., and Brivanlou, A. H. (1996). In Vivo Evidence for Trigeminal Nerve Guidance by the Cement Gland in Xenopus. Developmental biology, 178(2), 363-374.
20. Lagna, G., Hata, A., Brivanlou, A. H., and Massague, J. (1996). Partnership between Dpc4 and Smad Proteins in Tgf-Β Signalling Pathways. Nature, 383(6603), 832-836. doi: 10.1038/383832a0
21. Weinstein, D. C., Rahman, S. M., Ruiz, J. C., and Brivanlou, A. H. (1996). Embryonic Expression of Eph Signalling Factors in Xenopus. Mechanisms of Development, 57(2), 133-144.
22. Altmann, C. R., Chow, R. L., Lang, R. A., and Brivanlou, A. H. (1997). Lens Induction by Pax-6 in Xenopus Laevis. Developmental biology, 185(1), 119-123. doi: 10.1006/dbio.1997.8573
23. Chang, C., Wilson, P. A., Mathews, L. S., and Brivanlou, A. H. (1997). A Xenopus Type I Activin Receptor Mediates Mesodermal but Not Neural Specification During Embryogenesis. Development, 124(4), 827-837.
24. de la Torre, J. R., Hopker, V. H., Ming, G. L., Poo, M. M., Tessier-Lavigne, M., Brivanlou, A. H., and Holt, C. E. (1997). Turning of Retinal Growth Cones in a Netrin-1 Gradient Mediated by the Netrin Receptor Dcc. Neuron, 19(6), 1211-1224.
25. Brivanlou, A. H., and Melton, D. (1997a). Vertebrate Embryonic Cells Will Become Nerve Cells Unless Told Otherwise. Cell, 88(1), 13-17.
26. Brivanlou, A. H., and Melton, D. (1997b). Vertebrate Neural Induction. Annual review of neuroscience, 20, 43-60. doi: 10.1146/annurev.neuro.20.1.43
27. Honoré, É., and Brivanlou, A. H. (1997). L'induction Neurale Chez Les Vertébrés: Le Cerveau Par Défaut. Medecine et Science, 13, 192-200.
28. Hoodless, P. A., and Brivanlou, A. H. (1997). Inhibitory Control of Neural Differentiation in Mammalian Cells. Development genes and evolution, 207(1), 19-28. doi: 10.1007/s004270050088
29. Lagna, G., and Brivanlou, A. H. (1997). Use of Dominant Negative Constructs to Modulate Gene Expression. Cellular and Molecular Procedures in Developmental Biology, 36, 75-96.
30. Suzuki, A., Chang, C., Yingling, J. M., Wang, X. F., and Brivanlou, A. H. (1997). Smad5 Induces Ventral Fates in Xenopus Embryo. Developmental biology, 184(2), 402-405. doi: 10.1006/dbio.1997.8548
31. Suzuki, A., Kaneko, E., Ueno, N., and Brivanlou, A. H. (1997). Regulation of Epidermal Induction by Bmp2 and Bmp7 Signaling. Developmental biology, 189(1), 112-122.
32. Suzuki, A., Ueno, N., and Brivanlou, A. H. (1997). Xenopus Msx1 Mediates Epidermal Induction and Neural Inhibition by Bmp4. Development, 124(16), 3037-3044.
33. Weinstein, D., Chang, C., Lagna, G., Suzuki, A., Wilson, P., and Brivanlou, A. H. (1997). Neural Induction in the Frog Xenopus Laevis Inhibin, Activin and Follistatin (pp. 214-219): Springer.
34. Weinstein, D. C., and Brivanlou, A. H. (1997). Neural Induction in Xenopus Laevis: Evidence for the Default Model. Current opinion in neurobiology, 7(1), 7-12.
35. Weinstein, D. C., Honore, E., and Brivanlou, A. H. (1997). Epidermal Induction and Inhibition of Neural Fate by Translation Initiation Factor 4aiii. Development, 124(21), 4235-4242.
36. Wilson, P. A., and Brivanlou, A. H. (1997). Vertebrate Neural Induction: Inducers, Inhibitors, and a New Synthesis. Neuron, 18(5), 699-710.
37. Wilson, P. A., Lagna, G., Suzuki, A., and Brivanlou, A. H. (1997). Concentration-Dependent Patterning of the Xenopus Ectoderm by Bmp4 and Its Signal Transducer Smad1. Development, 124(16), 3177-3184.
38. Brivanlou, A. H. (1998). Should the Master Regulator Rest in Peace? Nature genetics, 20(2), 109-110. doi: 10.1038/2402
39. Casellas, R., and Brivanlou, A. H. (1998). Xenopus Smad7 Inhibits Both the Activin and Bmp Pathways and Acts as a Neural Inducer. Developmental biology, 198(1), 1-12.
40. Chang, C., and Brivanlou, A. H. (1998a). Neural Crest Induction by Xwnt7b in Xenopus. Developmental biology, 194(1), 129-134. doi: 10.1006/dbio.1997.8820
41. Chang, C., and Brivanlou, A. H. (1998b). Cell Fate Determination in Embryonic Ectoderm. Journal of neurobiology, 36(2), 128-151.
42. Hata, A., Lagna, G., Massague, J., and Brivanlou, A. H. (1998). Smad6 Inhibits Bmp/Smad1 Signaling by Specifically Competing with the Smad4 Tumor Suppressor. Genes & development, 12(2), 186-197.
43. Mailhos, C., Andre, S., Mollereau, B., Goriely, A., Brivanlou, A. H., and Desplan, C. (1998). Drosophila Goosecoid Requires a Conserved Heptapeptide for Repression of Paired-Class Homeoprotein Activators. Development, 125(5), 937-947.
44. Weinstein, D. C., Marden, J., Carnevali, F., and Brivanlou, A. H. (1998). Fgf-Mediated Mesoderm Induction Involves the Src-Family Kinase Laloo. Nature, 394(6696), 904-908. doi: 10.1038/29808
45. Williams, S. C., Altmann, C. R., Chow, R. L., Brivanlou, A. H., and Lang, R. A. (1998). A Highly Conserved Lens Transcriptional Control Element from the Pax-6 Gene. Mech Dev, 73(2), 225-229.
46. Chang, C., and Brivanlou, A. H. (1999). Xenopus Gdf6, a New Antagonist of Noggin and a Partner of Bmps. Development, 126(15), 3347-3357.
47. Chow, R. L., Altmann, C. R., Lang, R. A., and Brivanlou, A. H. (1999). Pax6 Induces Ectopic Eyes in a Vertebrate. Development, 126(19), 4213-4222.
48. Brivanlou, A. H. (1999). Xenopus. Encyclopedia of Molecular Biology, 2793-2803.
49. Lagna, G., Carnevali, F., Marchioni, M., and Brivanlou, A. H. (1999). Negative Regulation of Axis Formation and Wnt Signaling in Xenopus Embryos by the F-Box/Wd40 Protein Β Trcp. Mech Dev, 80(1), 101-106.
50. Lagna, G., and Brivanlou, A. H. (1999). A Molecular Basis for Smad Specificity. Developmental dynamics : an official publication of the American Association of Anatomists, 214(3), 269-277. doi: 10.1002/(sici)1097-0177(199903)214:3<269::aid-aja10>3.0.co;2-#
51. Reissmann, E., and Brivanlou, A. H. (1999). Neuronal Subtype Identity Regulation. eLS.
52. Weinstein, D. C., and Brivanlou, A. H. (1999). Neural Induction. Annual review of cell and developmental biology, 15, 411-433. doi: 10.1146/annurev.cellbio.15.1.411
53. Altmann, C. R., Bell, E., and Brivanlou, A. H. (2000). Genomics and Embryology in Amphibians. Genome biology, 1(5), 4022.4022.
54. Chang, C., and Brivanlou, A. H. (2000). A Post-Mid-Blastula Transition Requirement for Tgfβ Signaling in Early Endodermal Specification. Mech Dev, 90(2), 227-235.
55. Hata, A., Seoane, J., Lagna, G., Montalvo, E., Brivanlou, A. H., and Massague, J. (2000). Oaz Uses Distinct DNA- and Protein-Binding Zinc Fingers in Separate Bmp-Smad and Olf Signaling Pathways. Cell, 100(2), 229-240.
56. Brivanlou, A. H. (2000). La Morphogenèse Du Système Nerveux Chez Les Vertébrés. Medecine et Science, 16, 150-158.
57. Suzuki, A., and Brivanlou, A. H. (2000). Xenopus Embryonic E2f Is Required for the Formation of Ventral and Posterior Cell Fates During Early Embryogenesis. Molecular cell, 5(2), 217-229.
58. Altmann, C. R., Bell, E., Sczyrba, A., Pun, J., Bekiranov, S., Gaasterland, T., and Brivanlou, A. H. (2001). Microarray-Based Analysis of Early Development in Xenopus Laevis. Developmental biology, 236(1), 64-75. doi: 10.1006/dbio.2001.0298
59. Altmann, C. R., and Brivanlou, A. H. (2001). Neural Patterning in the Vertebrate Embryo. International review of cytology, 203, 447-482.
60. Chang, C., Holtzman, D. A., Chau, S., Chickering, T., Woolf, E. A., Holmgren, L. M., Bodorova, J., Gearing, D. P., Holmes, W. E., and Brivanlou, A. H. (2001). Twisted Gastrulation Can Function as a Bmp Antagonist. Nature, 410(6827), 483-487. doi: 10.1038/35068583
61. Eggen, B. J., and Brivanlou, A. H. (2001). Bmp Antagonists and Neural Induction. eLS.
62. Munoz-Sanjuan, I., and Brivanlou, A. H. (2001). Early Posterior/Ventral Fate Specification in the Vertebrate Embryo. Developmental biology, 237(1), 1-17. doi: 10.1006/dbio.2001.0350
63. Reissmann, E., Jornvall, H., Blokzijl, A., Andersson, O., Chang, C., Minchiotti, G., Persico, M. G., Ibanez, C. F., and Brivanlou, A. H. (2001). The Orphan Receptor Alk7 and the Activin Receptor Alk4 Mediate Signaling by Nodal Proteins During Vertebrate Development. Genes & development, 15(15), 2010-2022. doi: 10.1101/gad.201801
64. Weinstein, D. C., and Brivanlou, A. H. A. (2001). Src Family Kinase Function During Early Xenopus Development. Developmental dynamics : an official publication of the American Association of Anatomists, 220(2), 163-168. doi: 10.1002/1097-0177(2000)9999:9999<1::aid-dvdy1098>3.0.co;2-5
65. Zhang, Y., Chang, C., Gehling, D. J., Brivanlou, A. H., and Derynck, R. (2001). Regulation of Smad Degradation and Activity by Smurf2, an E3 Ubiquitin Ligase. Proceedings of the National Academy of Sciences, 98(3), 974-979.
66. Zohn, I. E., and Brivanlou, A. H. (2001). Expression Cloning of Xenopus Os4, an Evolutionarily Conserved Gene, Which Induces Mesoderm and Dorsal Axis. Developmental biology, 239(1), 118-131. doi: 10.1006/dbio.2001.0420
67. Altmann, C., and Brivanlou, A. H. (2002). Microarrays: Common Ground for Biologists and Physicists. nature neuroscience, 5(10), 931-931.
68. Altmann, C. R., Chang, C., Munoz-Sanjuan, I., Bell, E., Heke, M., Rifkin, D. B., and Brivanlou, A. H. (2002). The Latent-Tgfβ-Binding-Protein-1 (Ltbp-1) Is Expressed in the Organizer and Regulates Nodal and Activin Signaling. Developmental biology, 248(1), 118-127.
69. Brivanlou, A. H., and Darnell, J. E., Jr. (2002). Signal Transduction and the Control of Gene Expression. Science, 295(5556), 813-818. doi: 10.1126/science.1066355
70. Domingos, P. M., Obukhanych, T. V., Altmann, C. R., and Brivanlou, A. H. (2002). Cloning and Developmental Expression of Baf57 in Xenopus Laevis. Mech Dev, 116(1-2), 177-181.
71. Dubertret, B., Skourides, P., Norris, D. J., Noireaux, V., Brivanlou, A. H., and Libchaber, A. (2002). In Vivo Imaging of Quantum Dots Encapsulated in Phospholipid Micelles. Science, 298(5599), 1759-1762. doi: 10.1126/science.1077194
72. Munoz-Sanjuan, I., Bell, E., Altmann, C. R., Vonica, A., and Brivanlou, A. H. (2002). Gene Profiling During Neural Induction in Xenopus Laevis: Regulation of Bmp Signaling by Post-Transcriptional Mechanisms and Tab3, a Novel Tak1-Binding Protein. Development, 129(23), 5529-5540.
73. Munoz-Sanjuan, I., and Brivanlou, A. H. (2002). Neural Induction, the Default Model and Embryonic Stem Cells. Nature reviews. Neuroscience, 3(4), 271-280. doi: 10.1038/nrn786
74. Rho, J., Altmann, C. R., Socci, N. D., Merkov, L., Kim, N., So, H., Lee, O., Takami, M., Brivanlou, A. H., and Choi, Y. (2002). Gene Expression Profiling of Osteoclast Differentiation by Combined Suppression Subtractive Hybridization (Ssh) and Cdna Microarray Analysis. DNA and cell biology, 21(8), 541-549. doi: 10.1089/104454902320308915
75. Bell, E., Munoz-Sanjuan, I., Altmann, C. R., Vonica, A., and Brivanlou, A. H. (2003). Cell Fate Specification and Competence by Coco, a Maternal Bmp, Tgfβ and Wnt Inhibitor. Development, 130(7), 1381-1389.
76. Brivanlou, A. H., Gage, F. H., Jaenisch, R., Jessell, T., Melton, D., and Rossant, J. (2003). Setting Standards for Human Embryonic Stem Cells. Science, 300, 913-916.
77. Chang, C., Eggen, B. J., Weinstein, D. C., and Brivanlou, A. H. (2003). Regulation of Nodal and Bmp Signaling by Tomoregulin-1 (X7365) through Novel Mechanisms. Developmental biology, 255(1), 1-11.
78. Cheng, S. K., Olale, F., Bennett, J. T., Brivanlou, A. H., and Schier, A. F. (2003). Egf-Cfc Proteins Are Essential Coreceptors for the Tgf-Β Signals Vg1 and Gdf1. Genes & development, 17(1), 31-36. doi: 10.1101/gad.1041203
79. Levine, A. J., Munoz-Sanjuan, I., Bell, E., North, A. J., and Brivanlou, A. H. (2003). Fluorescent Labeling of Endothelial Cells Allows in Vivo, Continuous Characterization of the Vascular Development of Xenopus Laevis. Developmental biology, 254(1), 50-67.
80. Meijer, L., Skaltsounis, A. L., Magiatis, P., Polychronopoulos, P., Knockaert, M., Leost, M., Ryan, X. P., Vonica, C. A., Brivanlou, A. H., Dajani, R., Crovace, C., Tarricone, C., Musacchio, A., Roe, S. M., Pearl, L., and Greengard, P. (2003). Gsk-3-Selective Inhibitors Derived from Tyrian Purple Indirubins. Chemistry & biology, 10(12), 1255-1266.
81. Sato, N., Sanjuan, I. M., Heke, M., Uchida, M., Naef, F., and Brivanlou, A. H. (2003). Molecular Signature of Human Embryonic Stem Cells and Its Comparison with the Mouse. Developmental biology, 260(2), 404-413.
82. Spagnoli, F. M., and Brivanlou, A. H. (2003). Molecules Take Center Stage. Development, 130, 5558-5559.
83. Bell, E., and Brivanlou, A. H. (2004). Molecular Patterning of the Embryonic Brain The Vertebrate Organizer (pp. 299-313): Springer.
84. Besser, D. (2004). Expression of Nodal, Lefty-a, and Lefty-B in Undifferentiated Human Embryonic Stem Cells Requires Activation of Smad2/3. The Journal of biological chemistry, 279(43), 45076-45084. doi: 10.1074/jbc.M404979200
85. Munoz-Sanjuan, I., and Brivanlou, A. H. (2004). Modulation of Bmp Signaling During Vertebrate Gastrulation. In C. Stern (Ed.), Gastrulation: From Cells to Embryo (pp. 475-504). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
86. Sato, N., Meijer, L., Skaltsounis, L., Greengard, P., and Brivanlou, A. H. (2004). Maintenance of Pluripotency in Human and Mouse Embryonic Stem Cells through Activation of Wnt Signaling by a Pharmacological Gsk-3-Specific Inhibitor. Nature medicine, 10(1), 55-63.
87. Talikka, M., Stefani, G., Brivanlou, A. H., and Zimmerman, K. (2004). Characterization of Xenopus Phox2a and Phox2b Defines Expression Domains within the Embryonic Nervous System and Early Heart Field. Gene expression patterns : GEP, 4(5), 601-607. doi: 10.1016/j.modgep.2004.01.012
88. Chamorro, M. N., Schwartz, D. R., Vonica, A., Brivanlou, A. H., Cho, K. R., and Varmus, H. E. (2005). Fgf-20 and Dkk1 Are Transcriptional Targets of Β-Catenin and Fgf-20 Is Implicated in Cancer and Development. The EMBO journal, 24(1), 73-84. doi: 10.1038/sj.emboj.7600460
89. James, D., Levine, A. J., Besser, D., and Brivanlou, A. H. (2005). Tgfβ/Activin/Nodal Signaling Is Necessary for the Maintenance of Pluripotency in Human Embryonic Stem Cells. Development, 132(6), 1273-1282. doi: 10.1242/dev.01706
90. Munoz-Sanjuan, I., and Brivanlou, A. H. (2005). Induction of Ectopic Olfactory Structures and Bone Morphogenetic Protein Inhibition by Rossy, a Group Xii Secreted Phospholipase A2. Molecular and cellular biology, 25(9), 3608-3619. doi: 10.1128/mcb.25.9.3608-3619.2005
91. Noggle, S. A., James, D., and Brivanlou, A. H. (2005). A Molecular Basis for Human Embryonic Stem Cell Pluripotency. Stem cell reviews, 1(2), 111-118.
92. Noggle, S. A., Sato, N., and Brivanlou, A. H. (2005). Feeder Free Culture of Human Embryonic Stem Cells. In A. Bongso & E. H. Lee (Eds.), Stem Cells: From Bench to Bedside (pp. 144-160): World Scientific Publishing Company.
93. Samad, T. A., Rebbapragada, A., Bell, E., Zhang, Y., Sidis, Y., Jeong, S. J., Campagna, J. A., Perusini, S., Fabrizio, D. A., Schneyer, A. L., Lin, H. Y., Brivanlou, A. H., Attisano, L., and Woolf, C. J. (2005). Dragon, a Bone Morphogenetic Protein Co-Receptor. The Journal of biological chemistry, 280(14), 14122-14129. doi: 10.1074/jbc.M410034200
94. Sczyrba, A., Beckstette, M., Brivanlou, A. H., Giegerich, R., and Altmann, C. R. (2005). Xendb: Full Length Cdna Prediction and Cross Species Mapping in Xenopus Laevis. BMC genomics, 6, 123. doi: 10.1186/1471-2164-6-123
95. Spagnoli, F. M., and Brivanlou, A. H. (2005). A Full Menu for Stem-Cell Research. Genome biology, 6(3), 311.
96. Suarez-Farinas, M., Noggle, S., Heke, M., Brivanlou, A. H., and Magnasco, M. O. (2005). Comparing Independent Microarray Studies: The Case of Human Embryonic Stem Cells. BMC genomics, 6, 99. doi: 10.1186/1471-2164-6-99
97. Wysocka, J., Swigut, T., Milne, T. A., Dou, Y., Zhang, X., Burlingame, A. L., Roeder, R. G., Brivanlou, A. H., and Allis, C. D. (2005). Wdr5 Associates with Histone H3 Methylated at K4 and Is Essential for H3 K4 Methylation and Vertebrate Development. Cell, 121(6), 859-872. doi: 10.1016/j.cell.2005.03.036
98. Chang, C., Brivanlou, A. H., and Harland, R. M. (2006). Function of the Two Xenopus Smad4s in Early Frog Development. The Journal of biological chemistry, 281(41), 30794-30803. doi: 10.1074/jbc.M607054200
99. James, D., Noggle, S. A., Swigut, T., and Brivanlou, A. H. (2006). Contribution of Human Embryonic Stem Cells to Mouse Blastocysts. Developmental biology, 295(1), 90-102. doi: 10.1016/j.ydbio.2006.03.026
100. Knockaert, M., and Brivanlou, A. H. (2006). Indirubin and Embryonic Stem Cells. In L. Meijer, N. Guyard, L. Skaltsounis & G. Eisenbrand (Eds.), Indirubin, the Red Shade of Indigo (pp. 269-277).
101. Knockaert, M., Sapkota, G., Alarcon, C., Massague, J., and Brivanlou, A. H. (2006). Unique Players in the Bmp Pathway: Small C-Terminal Domain Phosphatases Dephosphorylate Smad1 to Attenuate Bmp Signaling. Proceedings of the National Academy of Sciences of the United States of America, 103(32), 11940-11945. doi: 10.1073/pnas.0605133103
102. Levine, A. J., and Brivanlou, A. H. (2006a). Gdf3, a Bmp Inhibitor, Regulates Cell Fate in Stem Cells and Early Embryos. Development, 133(2), 209-216. doi: 10.1242/dev.02192
103. Levine, A. J., and Brivanlou, A. H. (2006b). Gdf3 at the Crossroads of Tgf-Β Signaling. Cell cycle, 5(10), 1069-1073.
104. Sapkota, G., Knockaert, M., Alarcon, C., Montalvo, E., Brivanlou, A. H., and Massague, J. (2006). Dephosphorylation of the Linker Regions of Smad1 and Smad2/3 by Small C-Terminal Domain Phosphatases Has Distinct Outcomes for Bone Morphogenetic Protein and Transforming Growth Factor-Β Pathways. The Journal of biological chemistry, 281(52), 40412-40419. doi: 10.1074/jbc.M610172200
105. Sato, N., and Brivanlou, A. H. (2006a). Microarray Approach to Identify the Signaling Network Responsible for Self-Renewal of Human Embryonic Stem Cells. Methods in molecular biology, 331, 267-283. doi: 10.1385/1-59745-046-4:267
106. Sato, N., and Brivanlou, A. H. (2006b). Manipulation of Self-Renewal in Human Embryonic Stem Cells through a Novel Pharmacological Gsk-3 Inhibitor. Methods in molecular biology, 331, 115-128. doi: 10.1385/1-59745-046-4:115
107. Spagnoli, F. M., and Brivanlou, A. H. (2006). The Rna-Binding Protein, Vg1rbp, Is Required for Pancreatic Fate Specification. Developmental biology, 292(2), 442-456.
108. Spagnoli, F. M., and Brivanlou, A. H. (2006). Guiding Embryonic Stem Cells Towards Differentiation: Lessons from Molecular Embryology. Current opinion in genetics & development, 16(5), 469-475. doi: 10.1016/j.gde.2006.08.004
109. Tabibzadeh, S., and Brivanlou, A. H. (2006). Lefty at the Crossroads of "Stemness" and Differentiative Events. Stem cells, 24(9), 1998-2006. doi: 10.1634/stemcells.2006-0075
110. Vonica, A., and Brivanlou, A. H. (2006). An Obligatory Caravanserai Stop on the Silk Road to Neural Induction: Inhibition of Bmp/Gdf Signaling. Seminars in cell & developmental biology, 17(1), 117-132. doi: 10.1016/j.semcdb.2005.11.013
111. Dreesen, O., and Brivanlou, A. H. (2007). Signaling Pathways in Cancer and Embryonic Stem Cells. Stem cell reviews, 3(1), 7-17.
112. Levine, A. J., and Brivanlou, A. H. (2007a). Molecular Basis of Pluripotency. In A. Atala & R. Lanza (Eds.), Principles of Regenerative Medicine (pp. 118-127): Academic Press.
113. Levine, A. J., and Brivanlou, A. H. (2007b). Proposal of a Model of Mammalian Neural Induction. Developmental biology, 308(2), 247-256. doi: 10.1016/j.ydbio.2007.05.036
114. Noggle, S., Spagnoli, F. M., and Brivanlou, A. H. (2007). In Vivo Assays for Human Embryonic Stem Cells. In S. Sullivan, C. A. Cowan & K. Eggan (Eds.), Human Embryonic Stem Cells: The Practical Handbook: John Wiley & Sons.
115. Sapkota, G., Alarcon, C., Spagnoli, F. M., Brivanlou, A. H., and Massague, J. (2007). Balancing Bmp Signaling through Integrated Inputs into the Smad1 Linker. Molecular cell, 25(3), 441-454. doi: 10.1016/j.molcel.2007.01.006
116. Vonica, A., and Brivanlou, A. H. (2007). The Left-Right Axis Is Regulated by the Interplay of Coco, Xnr1 and Derriere in Xenopus Embryos. Developmental biology, 303(1), 281-294. doi: 10.1016/j.ydbio.2006.09.039
117. Spagnoli, F. M., and Brivanlou, A. H. (2008). The Gata5 Target, Tgif2, Defines the Pancreatic Region by Modulating Bmp Signals within the Endoderm. Development, 135(3), 451-461. doi: 10.1242/dev.008458
118. Di Pasquale, E., and Brivanlou, A. H. (2009). Bone Morphogenetic Protein 15 (Bmp15) Acts as a Bmp and Wnt Inhibitor During Early Embryogenesis. The Journal of biological chemistry, 284(38), 26127-26136. doi: 10.1074/jbc.M109.036608
119. Francois, P., Vonica, A., Brivanlou, A. H., and Siggia, E. D. (2009). Scaling of Bmp Gradients in Xenopus Embryos. Nature, 461(7260), E1; discussion E2.
120. Lacoste, A., Berenshteyn, F., and Brivanlou, A. H. (2009). An Efficient and Reversible Transposable System for Gene Delivery and Lineage-Specific Differentiation in Human Embryonic Stem Cells. Cell stem cell, 5(3), 332-342. doi: 10.1016/j.stem.2009.07.011
121. Levine, A. J., Levine, Z. J., and Brivanlou, A. H. (2009). Gdf3 Is a Bmp Inhibitor That Can Activate Nodal Signaling Only at Very High Doses. Developmental biology, 325(1), 43-48. doi: 10.1016/j.ydbio.2008.09.006
122. Rosa, A., and Brivanlou, A. H. (2009). Micrornas in Early Vertebrate Development. Cell cycle, 8(21).
123. Rosa, A., Spagnoli, F. M., and Brivanlou, A. H. (2009). The Mir-430/427/302 Family Controls Mesendodermal Fate Specification Via Species-Specific Target Selection. Developmental cell, 16(4), 517-527. doi: 10.1016/j.devcel.2009.02.007
124. Yan, C. Y., Skourides, P., Chang, C., and Brivanlou, A. H. (2009). Samba, a Xenopus Hnrnp Expressed in Neural and Neural Crest Tissues. Developmental dynamics : an official publication of the American Association of Anatomists, 238(1), 204-209. doi: 10.1002/dvdy.21826
125. Rosa, A., and Brivanlou, A. H. (2010). Synthetic Mrnas: Powerful Tools for Reprogramming and Differentiation of Human Cells. Cell stem cell, 7(5), 549-550. doi: 10.1016/j.stem.2010.10.002
126. Shimomura, Y., Agalliu, D., Vonica, A., Luria, V., Wajid, M., Baumer, A., Belli, S., Petukhova, L., Schinzel, A., Brivanlou, A. H., Barres, B. A., and Christiano, A. M. (2010). Apcdd1 Is a Novel Wnt Inhibitor Mutated in Hereditary Hypotrichosis Simplex. Nature, 464(7291), 1043-1047. doi: 10.1038/nature08875
127. Singh, H., and Brivanlou, A. H. (2010). The Molecular Design of Pluripotency. In A. Atala, R. Lanza, J. A. Thomson & R. Nerem (Eds.), Principles of Regenerative Medicine, Second Edition (pp. 87-94): Academic Press.
128. Rosa, A., and Brivanlou, A. H. (2011). A Regulatory Circuitry Comprised of Mir-302 and the Transcription Factors Oct4 and Nr2f2 Regulates Human Embryonic Stem Cell Differentiation. The EMBO journal, 30(2), 237-248. doi: 10.1038/emboj.2010.319
129. Vonica, A., Rosa, A., Arduini, B. L., and Brivanlou, A. H. (2011). Apobec2, a Selective Inhibitor of Tgfβ Signaling, Regulates Left-Right Axis Specification During Early Embryogenesis. Developmental biology, 350(1), 13-23. doi: 10.1016/j.ydbio.2010.09.016
130. Arduini, B. L., and Brivanlou, A. H. (2012). Modulation of Foxd3 Activity in Human Embryonic Stem Cells Directs Pluripotency and Paraxial Mesoderm Fates. Stem cells, 30(10), 2188-2198. doi: 10.1002/stem.1200
131. Gao, H., Chakraborty, G., Lee-Lim, A. P., Mo, Q., Decker, M., Vonica, A., Shen, R., Brogi, E., Brivanlou, A. H., and Giancotti, F. G. (2012). The Bmp Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic Sites. Cell, 150(4), 764-779. doi: 10.1016/j.cell.2012.06.035
132. Hata, A., and Brivanlou, A. H. (2012). A Taste of Tgfβ in Tuscany. Development, 139(3), 449-453. doi: 10.1242/dev.067249
133. Warmflash, A., Arduini, B. L., and Brivanlou, A. H. (2012). The Molecular Circuitry Underlying Pluripotency in Embryonic Stem Cells. Wiley interdisciplinary reviews. Systems biology and medicine, 4(5), 443-456. doi: 10.1002/wsbm.1182
134. Warmflash, A., Siggia, E. D., and Brivanlou, A. H. (2012). Signaling Dynamics and Embryonic Development. Cell cycle, 11(19), 3529-3530. doi: 10.4161/cc.21964
135. Warmflash, A., Zhang, Q., Sorre, B., Vonica, A., Siggia, E. D., and Brivanlou, A. H. (2012). Dynamics of Tgf-Β Signaling Reveal Adaptive and Pulsatile Behaviors Reflected in the Nuclear Localization of Transcription Factor Smad4. Proceedings of the National Academy of Sciences of the United States of America, 109(28), E1947-1956. doi: 10.1073/pnas.1207607109
136. Bates, T. J., Vonica, A., Heasman, J., Brivanlou, A. H., and Bell, E. (2013). Coco Regulates Dorsoventral Specification of Germ Layers Via Inhibition of Tgfβ Signalling. Development, 140(20), 4177-4181. doi: 10.1242/dev.095521
137. Kintner, C., and Brivanlou, A. H. (2013). Neural Induction Embryonic Stem Cells. In J. Rubenstein & P. Rakic (Eds.), Patterning and Cell Type Specification in the Developing CNS and PNS: Comprehensive Developmental Neuroscience (Vol. 1): Academic Press.
138. Ozair, M. Z., Kintner, C., and Brivanlou, A. H. (2013). Neural Induction and Early Patterning in Vertebrates. Wiley interdisciplinary reviews. Developmental biology, 2(4), 479-498. doi: 10.1002/wdev.90
139. Ozair, M. Z., Noggle, S., Warmflash, A., Krzyspiak, J. E., and Brivanlou, A. H. (2013). Smad7 Directly Converts Human Embryonic Stem Cells to Telencephalic Fate by a Default Mechanism. Stem cells, 31(1), 35-47. doi: 10.1002/stem.1246
140. Rosa, A., and Brivanlou, A. H. (2013). Regulatory Non-Coding Rnas in Pluripotent Stem Cells. International journal of molecular sciences, 14(7), 14346-14373. doi: 10.3390/ijms140714346
141. Whitman, M., Rosen, V., Brivanlou, A. H., Groppe, J. C., Sebald, W., and Mueller, T. (2013). Regarding the Mechanism of Action of a Proposed Peptide Agonist of the Bone Morphogenetic Protein Receptor Activin-Like Kinase 3. Nature medicine, 19(7), 809-810. doi: 10.1038/nm.3080
142. Rosa, A., Papaioannou, M. D., Krzyspiak, J. E., and Brivanlou, A. H. (2014). Mir-373 Is Regulated by Tgfβ Signaling and Promotes Mesendoderm Differentiation in Human Embryonic Stem Cells. Developmental biology. doi: 10.1016/j.ydbio.2014.03.020
143. Sorre, B., Warmflash, A., Brivanlou, A. H., and Siggia, E. D. (2013). Encoding of Temporal Signals by the TGF-β pathway and Implications for Embryonic Patterning (submitted).
144. Warmflash, A., Sorre, B., Etoc, F., Siggia, E. D., and Brivanlou, A. H. (2014). Recapitulation of Early Embryonic Spatial Patterning in Human Embryonic Stem Cells using Micropatterned Control of Colony Architecture (submitted).
145. Ismailoglu, I., Popowski, M., and Brivanlou, A. H. (2013). Discovery of Novel Isoforms of Huntington mRNAs Expressed in Human Embryonic Stem Cells (submitted).
146. Ismailoglu, I., Popowski, M., and Brivanlou, A. H. (2013). Huntingtin Affects Differentiation of hESCs by Modulating TGFβ Signaling (submitted).
147. Ismailoglu, I., Popowski, M., Chen, Q., Yang, L., Gross, S., and Brivanlou, A. H. (2014). Huntingtin Protein is Essential for Mitochondrial Metabolism, Bioenergetics and Structure in Murine Embryonic Stem Cells. Developmental biology. (in press)
